GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.08 | 2.45E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | EML5 | chr14:89081205-89259157:- | 0.29 | 6.69 | 6.16E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7 | 8.99E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.2 | 1.23E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.7 | 5.52E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983700 | chr9:100537455 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.2 | 1.22E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | BMPR1A | chr10:88516396-88684944:+ | -0.23 | -5.93 | 5.73E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | C10orf47 | chr10:11865397-11914274:+ | -0.22 | -5.89 | 7.32E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.14 | 1.69E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.76 | 4.15E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | EPDR1 | chr7:37960163-37991539:+ | 0.3 | 6.72 | 5.24E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.22 | 1.1E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.68 | 6.4E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983701 | chr9:100537577 | PLCE1 | chr10:95753746-96088146:+ | 0.28 | 6.27 | 8.31E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs10983761 | chr9:100553957 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.3 | 6.58E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |